Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| AC_Pat22 | RO.00.IS.22 | Romania | 2000 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV+ 3TC+ AZT | NA |
| 2 | None | NA |
| 3 | RTV+ NVP+ D4T | NA |
| 4 | NFV+ NVP+ D4T | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y181C | V35P, T39A, E40D, D123E, I135L, S162H, K173A, Q174R, D177E, I195L, T200A, Q207E, R211K |
| >RO.00.IS.22| codons 33-239 ALPEICADMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQL GIPHPAGLKKKKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSLNNETPGIRYQYNVLPQG WKGSPAIFQHSMTKILEPFRARNPEIVICQYMDDLYVGSDLELGQHRAKIEELREHLLKW GFTTPDKKHQKEPPFLWMGYELHPDKW |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A | L10V, I13V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, L89M |
| >RO.00.IS.22| codons 1-99 PQITLWQRPVVTVKVEGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVKQYD QITIDICGHKAIGTVLVGPTPANIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Apetrei, C | HIV type 1 diversity in northeastern Romania in 2000-2001 based on phylogenetic analysis of pol sequences from patients failing antiretroviral therapy. | ARHR, 2003 |