Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| AC_Pat21 | RO.01.IS.21 | Romania | 2001 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV+ 3TC+ AZT | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12I, I15V, K20R, E35D, M36I, R41K, K45R, R57K, L63T, E65D, L89M |
| >RO.01.IS.21| codons 1-99 PQITLWQRPLVIIKVGGQLREALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVKQYD QITIDICGHKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R | V35T, T39A, E40D, K49R, E53G, D123E, I135L, S162Y, E169A, K173T, Q174K, I195L, Q207E, R211K |
| >RO.01.IS.21| codons 33-239 ALTEICADMEKEGKISRIGPGNPYNTPVFAIKKKDSTRWRKLVDFRELNKRTQDFWEVQL GIPHPAGLKKKKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSLNNETPGIRYQYNVLPQG WKGSPAIFQYSMTKILAPFRTKNPDIVIYQYMDDLYVGSDLELGQHRTKIEELREHLLKW GFTTPDKKHQKEPPFLWMGYELHPDKW |
References
| Author | Title | Citation |
| Apetrei, C | HIV type 1 diversity in northeastern Romania in 2000-2001 based on phylogenetic analysis of pol sequences from patients failing antiretroviral therapy. | ARHR, 2003 |