<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
AC_Pat8 RO.01.IS.08 Romania 2001 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 IDV+ 3TC+ AZT NA
2 Unknown NA
3 NFV+ SQV+ D4T NA
4 IDV+ 3TC+ RTV NA
5 Unknown 4

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, Q18E, L19T, K20R, E35D, M36I, R41K, R57K, L63T, E65D  
>RO.01.IS.08| codons 1-99
PQITLWQRPLVSIKVGGETREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
QITIDICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   G190A V179D V35T, T39A, K46Q, D123E, I135L, I142V, S162H, K173T, Q174K, I195L, T200A, Q207T, R211K  
>RO.01.IS.08| codons 33-239
ALTEICAEMEKEGQISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQL
GIPHPAGLKKKKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSLNNETPGVRYQYNVLPQG
WKGSPAIFQHSMTKILEPFRTKNPDIDIYQYVDDLYVASDLELGQHRAKIEELRTHLLKW
GFTTPDKKHQKEPPFLWMGYELHPDKW

References
Author Title Citation
Apetrei, C HIV type 1 diversity in northeastern Romania in 2000-2001 based on phylogenetic analysis of pol sequences from patients failing antiretroviral therapy. ARHR, 2003