<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
AC_Pat7 RO.01.IS.07 Romania 2001 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 IDV+ 3TC+ AZT NA
2 None NA
3 NFV+ SQV+ 3TC NA
4 Unknown 69

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A   L10V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89M  
>RO.01.IS.07| codons 1-99
PQITLWQRPVVTIKVEGQLREALLDTGADDTVLEDINLPGKWKPKLIGGIGGFVKVKQYD
QITIDICGHKATGTVLVGPTPANIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70R T215I, K219E K103N, Y181C   V35T, T39A, E40D, D123E, I135L, E138Q, I142T, S162H, K173A, Q174K, I195L, T200A, I202V, Q207A, H208Y, R211K, L228H  
>RO.01.IS.07| codons 33-239
ALTEICADMEKEGKISKIGPENPYNTPVFAIKKKDSTRWRKLVDFRELNKRTQDFWEVQL
GIPHPAGLKKNKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSLNNQTPGTRYQYNVLPQG
WKGSPAIFQHSMTKILEPFRAKNPDIVICQYMDDLYVGSDLELGQHRAKVEELRAYLLKW
GFITPDEKHQKEPPFHWMGYELHPDKW

References
Author Title Citation
Apetrei, C HIV type 1 diversity in northeastern Romania in 2000-2001 based on phylogenetic analysis of pol sequences from patients failing antiretroviral therapy. ARHR, 2003