<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
AC_Pat6 RO.01.IS.06 Romania 2001 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 IDV+ 3TC+ AZT NA
2 None NA
3 NVP+ RTV+ D4T NA
4 NVP+ NFV+ D4T NA
5 Unknown 4

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
  T215C K103N   V35T, D123E, I135L, S162Y, K166R, K173T, Q174R, I195L, T200A, Q207T, R211K  
>RO.01.IS.06| codons 33-239
ALTEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQL
GIPHPAGLKKNKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSLNNETPGIRYQYNVLPQG
WKGSPAIFQYSMTRILEPFRTRNPDIVIYQYMDDLYVGSDLELGQHRAKIEELRTHLLKW
GFCTPDKKHQKEPPFLWMGYELHPDKW

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I15V, L19I, K20T, E35D, M36I, R41K, R57K, I62V, L63T, E65D, V82I, L89M, I93L, F99Y  
>RO.01.IS.06| codons 1-99
PQITLWQRPVVTIKVGGQITEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
QVTIDICGHKAIGTVLVGPTPINIIGRNMLTQLGCTLNY

References
Author Title Citation
Apetrei, C HIV type 1 diversity in northeastern Romania in 2000-2001 based on phylogenetic analysis of pol sequences from patients failing antiretroviral therapy. ARHR, 2003