Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| AC_Pat4 | RO.00.IS.04 | Romania | 2000 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV+ 3TC+ AZT | NA |
| 2 | None | NA |
| 3 | NFV+ SQV+ D4T | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, T12S, I13V, I15V, G16E, K20R, E35D, M36I, R41K, R57K, L63T, E65D, I72T, L89M |
| >RO.00.IS.04| codons 1-99 PQITLWQRPVVSVKVEGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QITIDICGHKATGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L | T215C | V35I, T39A, E40D, D123E, I135L, K173T, Q174K, D177E, T200E, Q207A, R211K |
| >RO.00.IS.04| codons 33-239 ALIEICADLEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQL GIPHPAGLKKKKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSLNNETPGIRYQYNVLPQG WKGSPAIFQSSMTKILEPFRTKNPEIVIYQYMDDLYVGSDLEIGQHREKIEELRAHLLKW GFCTPDKKHQKEPPFLWMGYELHPDKW |
References
| Author | Title | Citation |
| Apetrei, C | HIV type 1 diversity in northeastern Romania in 2000-2001 based on phylogenetic analysis of pol sequences from patients failing antiretroviral therapy. | ARHR, 2003 |