Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patPAL | 01_PAL708 | France | 2001 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 156 |
| 2 | None | 91 |
| 3 | DDI+ AZT | 21 |
| 4 | SQV+ DDI+ AZT | 34 |
| 5 | SQV+ AZT+ 3TC | 30 |
| 6 | SQV+ RTV+ D4T | 43 |
| 7 | NVP+ NFV+ DDI+ D4T | 52 |
| 8 | SQV+ NVP+ AZT+ 3TC | 21 |
| 9 | SQV+ RTV+ NVP+ AZT+ 3TC | 71 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, V75M, M184V, L210W, T215Y | K219N | K103N, Y181C | P9S, V35T, T39K, K43A, E44D, K49R, V60I, K122E, I142V, S162D, Q174N, D177E, T200A, Q207N | I159L |
| >01_PAL708| codons 1-241 PISPIETVSVKLKPGMDGPKVKQWPLTEEKIKALTEICKELEADGKISRIGPENPYNTPI FAIKKKNSTKWRKLMDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPALFQDSMTKILEPFRKNNPEIVI CQYVDDLYVGSDLEIGQHRAKIEELRNHLWRWGFYTPDNKHQKEPPFLWMGYELHPDKWT V |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N, M46L, I54V, L90M | L33I, N88D, L89V | I13V, K20I, M36I, N37K, L63P, C67S, H69K, A71V |
| >01_PAL708| codons 1-99 PQITLWQRPLVTVKIGGQLIEALLDTGADNTVIEEIKLPGRWKPKLIGGIGGFVKVRQYD QIPIEISGKKVIGTVLVGPTPVNIIGRDVMTQIGCTLNF |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |