Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patKON | 00_KON723 | France | 2000 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 39 |
| 2 | DDI+ AZT | 4 |
| 3 | IDV+ D4T+ 3TC | 52 |
| 4 | NFV+ D4T+ 3TC | 65 |
| 5 | NVP+ DDI+ D4T | 30 |
| 6 | NVP+ DDC+ D4T+ ABC | 12 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V | L10V, I13V, K14R, K20I, E35G, M36I, R41K, I64M, H69K, A71V, L89I |
| >00_KON723| codons 1-99 PQITLWQRPVVTVRIGGQLIEALLDTGADDTVLEGINLPGKWKPKMIGGIGGFVKVRQYD QILMEICGKKVIGTVLVGPTPVNIIGRNILTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, M184V, T215F | Y181C, G190A | V35T, E36A, T39K, K43E, D121H, K122E, D123S, I142V, S162F, K173S, Q174K, D177E, I178L, V179I, T200A, E203K, Q207D, H208Y, H221Y | K223N |
| >00_KON723| codons 1-224 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICKELEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL HESFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQFSMTKILEPFRSKNPELII CQYVDDLYVASDLEIGQHRAKIKELRDYLLRWGFFTPDKKYQNE |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |