Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patCAST | 00_CAST712 | France | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDC+ AZT | 169 |
| 2 | NVP+ DDI+ D4T | 30 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, T215Y | V106A, Y181C, G190A | V35M, V60I, I135T, T200A, E204D, R211Q, D218E |
| >00_CAST712| codons 17-239 DGPKVKQWPLTEEKIKALMEICTELEKEGKISKIGPENPYNTPIFAIKKKNSTRWRKLVD FRELNKRTQDFWEVQLGIPHPAGLKKKKSATVLDVGDAYFSVPLDKDFRKYTAFTIPSTN NETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVICQYMDDLYVASDLEIG QHRAKIEDLRQHLLQWGFYTPEKKHQKEPPFLWMGYELHPDKW |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |