<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
MB_patTICHET P 00_TIC715 France 2000 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 DDI+ AZT 65
2 D4T+ 3TC 130

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, M184V, T215Y K219E     K49R, S68G, S162D, E169D, D177E, T240A  
>00_TIC715| codons 14-242
PGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISRIGPENPYNTPVFAIKKKNGTRWRK
LVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIP
SINNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILDPFRKQNPEIVIYQYVDDLYVGSDL
EIGQHRTKIEELRQHLLRWGFYTPDEKHQKEPPFLWMGYELHPDKWAVQ

References
Author Title Citation
Montes, B Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. JAIDS, 2004
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005