<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
MB_patDEL 02_DEL707 France 2002 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 DDI+ AZT 156
2 NVP+ DDI+ AZT 8
3 NVP+ D4T+ 3TC 39
4 RTV+ IDV+ DDI+ ABC 21
5 AZT+ ABC+ 3TC 57
6 Unknown 21

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, M184V, T215Y K219E K103N   V35T, T39L, V60I, W88C, V90I, K101Q, V118I, K122E, D123S, I135T, E138A, K173T, Q174K, D177E, T200A, E203D, Q207D, R211K, F214L  
>02_DEL707| codons 1-237
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICLELEKEGKISKIGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFCEIQLGIPHPAGLQKNKSVTVLDVGDAYFSIPL
DESFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIVI
YQYVDDLYVGSDLEIGQHRAKIDELRDHLLKWGLYTPDEKHQKEPPFLWMGYELHPD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, K20I, E35D, M36I, R41K, K45R, R57K, L63S, I64M, C67E, H69K, V82I, L89M  
>02_DEL707| codons 1-99
PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVKQYD
QISMEIEGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Montes, B Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. JAIDS, 2004