Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patDEL | 01_DEL725 | France | 2001 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI+ AZT | 156 |
| 2 | NVP+ DDI+ AZT | 8 |
| 3 | NVP+ D4T+ 3TC | 39 |
| 4 | RTV+ IDV+ DDI+ ABC | 21 |
| 5 | AZT+ ABC+ 3TC | 25 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, K20I, E35D, M36I, R41K, K45R, R57K, L63S, C67E, H69K, V82I, L89M |
| >01_DEL725| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVKQYD QISIEIEGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, M184V, T215Y | K219E | K103N | V35T, T39L, V60I, W88C, K101Q, V118I, K122E, D123S, I135T, E138A, K173T, Q174K, D177E, T200A, E203D, Q207D, R211K, F214L |
| >01_DEL725| codons 1-242 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICLELEKEGKISKIGPENPYNTPI FAIKKKNSTRWRKLVDFRELNKRTQDFCEVQLGIPHPAGLQKNKSVTVLDVGDAYFSIPL DESFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIVI YQYVDDLYVGSDLEIGQHRAKIDELRDHLLKWGLYTPDEKHQKEPPFLWMGYELHPDKWT VQ |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |