Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patCOU | 02_COUL707 | France | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 187 |
| 2 | SQV+ DDI+ D4T | 30 |
| 3 | RTV+ D4T+ 3TC | 21 |
| 4 | IDV+ D4T+ 3TC | 13 |
| 5 | NFV+ IDV+ DDI | 21 |
| 6 | IDV+ EFV+ ABC | 136 |
| 7 | ABC | 57 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | G73S | L10I, T12S, I15V, K20T, M36I, R41K, L63P, H69K, A71V, I93L |
| >02_COUL707| codons 1-99 PQITLWQRPIVSIKVGGQLTEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKKVISTVLVGPTPVNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T69S_VG, K70R | V35T, E36A, T39D, K122E, D123S, I135T, K173A, Q174K, D177E, T200A, Q207E, R211K |
| >02_COUL707| codons 1-239 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICDEMEKEGKISKIGPENPYNTPV FAIKKKDSSRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKW |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |