Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patCOR | 01_CORN708 | France | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDC+ AZT | 52 |
| 2 | D4T+ 3TC | 52 |
| 3 | SQV+ RTV+ EFV+ D4T+ ABC+ 3TC | 4 |
| 4 | SQV+ RTV+ EFV+ ABC | 56 |
| 5 | None | 8 |
| 6 | LPV+ DDI+ 3TC | 34 |
| 7 | RTV+ DDI+ APV | 17 |
| 8 | DDI | 4 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, G48V, I50V, I54T, V82A | L33F | L10I, E34Q, E35D, M36I, N37D, L63P, A71V, I93L |
| >01_CORN708| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVFQDIDLPGRWKPKIIVGVGGFTKVRQYD QIPIEICGHKVIGTVLVGPTPANIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L210W, T215F | Y181C, G190A | A98G, V179D | V35I, T39A, E40F, K43E, K103R, V118I, K122E, S162A, G196E, T200I, E203D, L205F, Q207E, H208Y, R211K, E224D, L228H |
| >01_CORN708| codons 1-239 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICAFLEEEGKISKIGPENPYNTPV FAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKRKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRKQNPDIDI CQYMDDLYVASDLEIEQHRIKIDEFREYLWKWGFFTPDKKHQKDPPFHWMGYELHPDKW |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |