Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patBOUI | 01_BOUI703 | France | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 78 |
| 2 | AZT+ DDC | 43 |
| 3 | 3TC+ AZT+ RTV | 4 |
| 4 | 3TC+ AZT+ IDV | 134 |
| 5 | 3TC+ AZT+ NFV | 82 |
| 6 | DDC+ EFV+ SQV | 36 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | N88D | L10I, L63P, I64L, H69Q, T74S, V77I |
| >01_BOUI703| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADNTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QIPLEICGQKAIGSVLIGPTPVNIIGRDLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, T215Y | K219Q | K103N, Y181C | K101N | D123E, I142V, K166R, I178M, Q197L |
| >01_BOUI703| codons 1-242 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLNKNKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDMVI CQYMDDLYVGSDLEIGLHRTKIEELRQHLLRWGFYTPDQKHQKEPPFLWMGYELHPDKWT VQ |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |