Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patRAM | 02_RAM705 | France | 2002 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 47 |
| 2 | Unknown | 165 |
| 3 | 3TC+AZT | 73 |
| 4 | Unknown | 92 |
| 5 | 3TC+D4T+RTV | 40 |
| 6 | 3TC+D4T | 6 |
| 7 | 3TC+D4T+IDV | 49 |
| 8 | 3TC+D4T+IDV+RTV | 7 |
| 9 | 3TC+D4T+RTV | 24 |
| 10 | EFV | 25 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, G48V, I54V, V82T | L10V, I13V, K20I, M36I, N37D, R41K, I66F, H69K, K70R, L89M |
| >02_RAM705| codons 1-99 PQITLWQRPVVTVKIGGQLIEALLDTGADDTVLEEIDLPGKWKPKLIVGIGGFVKVRQYD QILIEFCGKRAIGTVLVGPTPTNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, M184V | K103N, Y188L | V35T, E40D, K43R, V60I, A98S, K122E, D123S, I135T, E138A, S162A, K173T, Q174K, T200A, Q207E, F214L | W24V, P25A |
| >02_RAM705| codons 1-238 PISPIETVPVKLKPGMDGPKVKQVALTEEKIKALTEICTDMEREGKISKIGPENPYNTPI FAIKKKDSTRWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPDIVI YQYVDDLLVGSDLEIGQHRAKIEELREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDK |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |