Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patGONO | 00_GONO705 | France | 2000 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NFV+ AZT | 16 |
| 2 | NFV+ AZT+ 3TC | 29 |
| 3 | NVP+ AZT+ 3TC | 3 |
| 4 | NVP+ NFV+ AZT+ 3TC | 18 |
| 5 | NFV+ AZT+ 3TC | 3 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13A, K14R, K20I, M36I, R41K, H69K, L89M |
| >00_GONO705| codons 1-99 PQITLWQRPLVTARIGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| P4S, E44D, I135V, Q145V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, H235P | G45L, P55Q |
| >00_GONO705| codons 1-239 PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKDLKISKIGPENQYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGIRYVYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEMVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELPPDKW |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |