Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patSER | 00_SER718 | France | 2000 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 35 |
| 2 | AZT+ DDC | 73 |
| 3 | 3TC+ D4T | 47 |
| 4 | None | 39 |
| 5 | D4T+ DDI+ SQV | 26 |
| 6 | ABC+ D4T+ NFV | 17 |
| 7 | None | 4 |
| 8 | ABC+ DDC+ EFV | 17 |
| 9 | 3TC+ AZT+ DDI+ EFV | 13 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, I15V, K20I, M36I, R41K, H69K, L89M |
| >00_SER718| codons 1-99 PQITLWQRPLVTVRVGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, Q151M, M184V | A62V, V75I, F77L, F116Y | K103N | P225H | K20R, V35T, T39A, E40D, S68G, T69I, R125K, I135L, S162A, T165A, K173T, Q174K, T200A, I202V, Q207D |
| >00_SER718| codons 1-236 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICADMEKEGKISKIGPENPYNTPV FVIKRKDGIKWRKLIDLRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYYSVPL DKDFKKYTAFTIPSLNNETPGIRYQYNVLPMGWKGSPAIFQASMAKILEPFRTKNPDIVI YQYVDDLYVGSDLEIGQHRAKVEELRDHLLRWGFTTPDKKHQKEHPFLWMGYELHP |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |