Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patMOL | 00_MOLL719 | France | 1999 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 104 |
| 2 | DDI+ AZT | 35 |
| 3 | AZT+ 3TC | 65 |
| 4 | SQV+ DDC+ AZT | 56 |
| 5 | RTV+ DDI+ D4T | 17 |
| 6 | IDV+ DDI+ D4T | 52 |
| 7 | NVP+ DDI+ D4T | 20 |
| 8 | NVP+ DDI+ D4T+ AZT+ 3TC | 1 |
| 9 | NVP+ DDI+ D4T | 3 |
| 10 | NVP+ NFV+ DDI+ D4T | 18 |
| 11 | NVP+ DDI+ D4T | 4 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | Q7E, E35D, M36I, P39Q, R41K, I62V, L63P, I64L, A71V, I72V, V77I, I93L |
| >00_MOLL719| codons 1-99 PQITLWERPLVTIKIGGQLKEALLDTGADNTVLEDINLQGKWKPKMIGGIGGFIKVRQYD QVPLEICGHKVVGTVLIGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, K49R, V60I, K122E, D177E, Q207E |
| >00_MOLL719| codons 1-242 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI YQYMDDLYVGSDLEIGQHRTKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQ |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |