Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patROU | 00_ROUX701 | France | 2000 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 126 |
| 2 | Unknown | 182 |
| 3 | AZT+DDI | 15 |
| 4 | 3TC+AZT | 14 |
| 5 | None | 172 |
| 6 | 3TC+AZT+NVP | 6 |
| 7 | None | 5 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, M184V, T215Y | K219E | Y181C | A98G, V108I | V60I, L109I, I135V, S162A, K173T, Q174E, D177E, T200A, I202V, Q207E, V245A, E248K, D250E |
| >00_ROUX701| codons 1-250 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPI FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTIIDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTENPEIVI CQYVDDLYVGSDLEIGQHRAKVEELREHLLRWGFYTPDEKHQKEPPFLWMGYELHPDKWT VQPIALPKKE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, K20I, M36I, N37D, L38I, R41K, L63S, I64M, H69K, L89M |
| >00_ROUX701| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEEIDIPGKWKPKMIGGIGGFIKVRQYD QISMEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |