Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patALI | 02_ALI705 | France | 2002 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT|DDI | 6 |
| 2 | DDI | 5 |
| 3 | None | 6 |
| 4 | D4T+DDI | 17 |
| 5 | None | 14 |
| 6 | 3TC+AZT+DDI | 18 |
| 7 | None | 15 |
| 8 | 3TC+AZT+NFV | 14 |
| 9 | 3TC+AZT+EFV | 28 |
| 10 | 3TC+AZT+EFV | 11 |
| 11 | None | 4 |
| 12 | 3TC+D4T+NVP | 6 |
| 13 | 3TC+D4T+NFV | 2 |
| 14 | 3TC+D4T | 8 |
| 15 | AZT+DDI | 7 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12E, I13V, K14R, G17E, K20I, M36I, L63P, I64L, H69K, L89M |
| >02_ALI705| codons 1-99 PQITLWQRPLVEVRIGEQLIEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYD QIPLEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K219E | K103N, Y181C | K20R, E36D, I135V, S162A, K173A, Q174K, D177E, T200A, Q207E, R211K |
| >02_ALI705| codons 1-240 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVDICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRAKNPEIVI CQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDEKHQKEPPFLWMGYELHPDKWT |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |