Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patROI | 00_ROI705 | France | 2000 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI+ AZT | 17 |
| 2 | SQV+ DDI+ AZT | 13 |
| 3 | SQV+ D4T+ 3TC | 21 |
| 4 | SQV+ RTV+ D4T | 13 |
| 5 | IDV+ DDI+ D4T | 146 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, G16E, K20R, M36I, R41K, L63N, H69K, K70R, L89I, T91V, I93L |
| >00_ROI705| codons 1-99 PQITLWQRPLVTVKIEGQLREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QINIEICGKRAIGTVLVGPTPVNIIGRNILVQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T27P, V35P, D121Y, K122E, D123E, I135T, I142V, K173S, Q174K, D177E, T200A, I202V, Q207A, R211K |
| >00_ROI705| codons 1-243 PISPIETVPVKLKPGMDGPKVKQWPLPEEKIKALPEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL YEEFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIVI YQYMDDLYVGSDLEIGQHRAKVEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQP |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |