Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patALC | 02_ALC723 | France | 2002 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI+ AZT | 39 |
| 2 | NFV+ DDI+ AZT | 35 |
| 3 | SQV+ RTV+ D4T+ 3TC | 56 |
| 4 | NVP+ DDI+ ABC | 136 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | K101E, G190A | V35T, E36D, T39K, K43A, E44D, V60I, K104R, D121H, K122E, D123S, I135R, I142V, S162Y, K173L, D177E, I178L, V179I, Q207A |
| >02_ALC723| codons 1-241 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICKELEADGKISKIGPENPYNTPI FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKRSVTVLDVGDAYFSVPL HESFRKYTAFTIPSRNNETPGVRYQYNVLPQGWKGSPAIFQYSMTKILEPFRLQNPELII YQYMDDLYVASDLEIGQHRTKIEELRAHLWRWGFYTPDKKHQKEPPFLWMGYELHPDKWT V |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I84V, L90M | L10I, I13V, K20I, E35D, M36I, R41K, K43R, L63P, H69K, A71V, L89I |
| >02_ALC723| codons 1-99 PQITLWQRPIVTVKIGGQLIEALLDTGADDTVLEDINLPGKWRPKMIGGIGGFIKVRQYD QIPIEICGKKVIGTVLVGPTPVNVIGRNIMTQIGCTLNF |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |