Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patBAR | 01_BAR714 | France | 2001 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 104 |
| 2 | DDI+ AZT | 261 |
| 3 | RTV+ DDI+ AZT | 104 |
| 4 | SQV+ RTV+ AZT | 17 |
| 5 | SQV+ AZT | 17 |
| 6 | SQV+ NFV+ AZT+ 3TC | 21 |
| 7 | SQV+ RTV+ AZT+ 3TC | 17 |
| 8 | SQV+ RTV+ NVP+ AZT+ 3TC | 8 |
| 9 | NFV+ EFV+ DDI+ D4T | 8 |
| 10 | RTV+ D4T+ APV+ ABC | 26 |
| 11 | LPV+ D4T+ ABC | 55 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V82A | L10I, K14Q, I15V, K20R, E35D, M36I, P39Q, R41K, R57K, Q61N, L63C, E65D, T74S, L89M |
| >01_BAR714| codons 1-99 PQITLWQRPIVTIQVGGQLREALLDTGADDTVLEDINLQGKWKPKMIGGIGGFIKVKQYD NICIDICGHKAIGSVLVGPTPANIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T215F | K103N, Y181C, G190A | V35T, K49R, I135L, S162C, E169D, K173A, Q174K, Q207E, R211K, L228R |
| >01_BAR714| codons 1-237 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRAKNPDIVI CQYMDDLYVASDLEIGQHRTKIEELREHLLKWGFFTPDKKHQKEPPFRWMGYELHPD |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |