Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patESTU | 01_ESTU702 | France | 2001 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDC | 21 |
| 2 | None | 13 |
| 3 | AZT+ 3TC | 17 |
| 4 | SQV+ DDC+ D4T+ AZT+ 3TC | 39 |
| 5 | RTV+ D4T+ AZT+ 3TC | 52 |
| 6 | NFV+ DDI+ AZT+ 3TC | 13 |
| 7 | NFV+ DDI+ AZT | 4 |
| 8 | NFV+ IDV+ AZT+ 3TC | 25 |
| 9 | NFV+ IDV+ DDI+ AZT | 21 |
| 10 | SQV+ RTV+ DDI+ D4T | 155 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | K219Q | V35T, T39A, K49R, V60I, V118I, K122E, S134N, I135T, T139I, I142T, D177E, I178M, Q207E |
| >01_ESTU702| codons 1-240 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICAELEKEGKISRIGPENPYNTPI FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPNTNNEIPGTRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMVI YQYMDDLYVGSDLEIGQHRTKIEELREHLWRWGFYTPDQKHQKEPPFLWMGYELHPDKWT |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I84V, L90M | V11I, G73S | L10V, I13V, K20I, L33V, I62V, L63P |
| >01_ESTU702| codons 1-99 PQITLWQRPVITVKIGGQLIEALLDTGADDTVVEEMNLPGRWKPKIIGGIGGFIKVRQYD QVPIEICGHKAISTVLVGPTPVNVIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |