Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patSANS | 02_SANS728 | France | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | RTV| IDV| EFV| D4T| AZT| APV| ABC| 3TC | 52 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54L, I84C | L10I, I15V, E35D, N37D, L63P |
| >02_SANS728| codons 1-99 PQITLWQRPIVTIKVGGQLKEALLDTGADDTVLEDMDLPGRWKPKLIGGIGGFLKVRQYD QIPIEICGHKAIGTVLVGPTPVNCIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V, T215F | K219Q | K103N, G190S | V35M, T39A, K49R, R83K, V118I, S162D, Q174H, I202V, E203A, Q207E, R211K, F214L, L228H | E79Q |
| >02_SANS728| codons 1-245 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICAEMEKEGKISRIGPENPYNTPV FAIKKKNSTRWRKLVDFRQLNKKTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILEPFRKHNPDIVI YQYVDDLYVSSDLEIGQHRTKVAELREHLLKWGLFTPDQKHQKEPPFHWMGYELHPDKWT VQPIV |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |