<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
MB_patHEN 01_HEN734 France 2001 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 NFV+ AZT+ ABC+ 3TC 4
2 NFV+ AZT+ ABC+ 3TC 56
3 LPV+ DDI+ ABC 2

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, L90M   I13V, K20I, E35G, M36I, R41K, H69K, K70R, V82I, L89M  
>01_HEN734| codons 1-99
PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEGINLPGKWKPKMIGGIGGFVKVRQYD
QILIEICGKRAIGTVLVGPTPINIIGRNMMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184I       V35T, T39A, E40D, K43R, V60I, A98S, K122E, D123S, I135T, E138A, I142V, S162A, K173T, Q174K, D177E, I178V, T200A, Q207E, R211S, F214L  
>01_HEN734| codons 1-241
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICADMEREGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNATPGVRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEVVI
YQYIDDLYVGSDLEIGQHRAKIEELREHLLSWGLTTPDKKHQKEPPFLWMGYELHPDKWT
V

References
Author Title Citation
Montes, B Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. JAIDS, 2004