Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patCLO | 00_CLO721 | France | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NFV+ AZT+ 3TC | 60 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| E35D, N37D, L63P, A71T, I72T |
| >00_CLO721| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDMDLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKTTGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K49R, D123E, S162C, E169D, E194Q, T200A | P25G, H235Q |
| >00_CLO721| codons 1-236 PISPIETVPVKLKPGMDGPKVKQWGLTEEKIKALVEICTEMEKEGKISRIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRKQNPDIVI YQYMDDLYVGSDLQIGQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELQP |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |