Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patGON | 02_GONC704 | France | 2002 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 30 |
| 2 | None | 25 |
| 3 | AZT | 141 |
| 4 | 3TC+AZT | 50 |
| 5 | None | 71 |
| 6 | 3TC+AZT+RTV | 4 |
| 7 | 3TC+D4T+RTV | 66 |
| 8 | None | 30 |
| 9 | 3TC+AZT+IDV+RTV | 29 |
| 10 | 3TC+AZT+LPV | 38 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, E35D, M36I, R41K, I62V, L63A |
| >02_GONC704| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QVAIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K20R, K32R, V35T, V60I, D121H, K122E, I135T, D177E, I178V, T200A, E204K, Q207E, F214L |
| >02_GONC704| codons 1-239 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIRALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEVVI YQYMDDLYVGSDLEIGQHRAKIEKLREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKW |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |