Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patLOP | 00_LOP710 | France | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | SQV| NVP| IDV| DDI| D4T| 3TC | 52 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | G73S | L10I, I13V, K14R, I15V, K20I, E35D, M36I, N37Q, R41K, I62V, L63P, A71T |
| >00_LOP710| codons 1-99 PQITLWQRPIVTVRVGGQLIEALLDTGADDTVLEDIQLPGKWKPKMIGGIGGFIKVRQYD QVPIEICGHKTISTVLVGPTPVNIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, M184V, L210W, T215Y | K219N | Y181C, G190A | V108I | V35I, T39A, S68G, K102Q, V118I, K122E, I135T, E203K, Q207E, H208Y, R211K |
| >00_LOP710| codons 1-243 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICAELEKEGKISKIGPENPYNTPV FAIKKKDGTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKQKKSVTILDVGDAYFSIPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI CQYVDDLYVASDLEIGQHRTKIKELREYLWKWGFYTPDNKHQKEPPFLWMGYELHPDKWT VQP |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |