Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patNIB | 01_NIB719 | France | 2001 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDI | 59 |
| 2 | 3TC+AZT | 61 |
| 3 | None | 19 |
| 4 | 3TC+DDI+NFV | 61 |
| 5 | 3TC+DDI+NFV | 17 |
| 6 | 3TC+AZT+DDI+NFV | 16 |
| 7 | None | 22 |
| 8 | ABC+AZT+DDI | 7 |
| 9 | 3TC+AZT+EFV | 9 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, L74V, M184V | L100I, K101E, K103N, V106M | K20R, V35T, E36A, T39E, S48T, K122E, D123N, K173A, D177E, T200A, Q207E, R211K |
| >01_NIB719| codons 1-241 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKRKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGIEKNKSMTVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT V |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | L23I | T12S, I13V, I15V, L19I, K20T, E35D, M36I, N37R, R41N, Q61E, L63A, I64M, H69K, V82I, L89M, I93L |
| >01_NIB719| codons 1-99 PQITLWQRPLVSVKVGGQITEAILDTGADDTVLEDIRLPGNWKPKMIGGIGGFIKVRQYD EIAMEICGKKAIGTVLVGPTPINIIGRNMMTQLGCTLNF |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |