Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patNIB | 01_NIB710 | France | 2001 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDI | 59 |
| 2 | 3TC+AZT | 61 |
| 3 | None | 19 |
| 4 | 3TC+DDI+NFV | 61 |
| 5 | 3TC+DDI+NFV | 17 |
| 6 | 3TC+AZT+DDI+NFV | 16 |
| 7 | None | 18 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I13V, I15V, L19I, M36I, N37K, R41N, Q61E, L63A, I64M, H69K, L89M, I93L |
| >01_NIB710| codons 1-99 PQITLWQRPLVSVKVGGQIKEALLDTGADDTVLEEIKLPGNWKPKMIGGIGGFIKVRQYD EIAMEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K20R, V35T, E36A, T39E, S48T, K122E, D123N, K173A, D177E, T200A, Q207E, R211K |
| >01_NIB710| codons 1-239 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKW |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |