Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patSAR | 02_SAR732 | France | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NFV| EFV| DDI| DDC| D4T| AZT| ABC| 3TC | 52 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, L74I, M184V, T215F | K219Q | K101P, K103N | D123E, I135T, G196E, I202V, F214L, D218E |
| >02_SAR732| codons 1-238 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKIVDFRELNKRTQDFWEVQLGIPHPAGLPKNKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIEQHRTKVEELRQHLLRWGLFTPEQKHQKEPPFLWMGYELHPDK |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | L33I, N88D | L10I, I15L, Q61E, L63P |
| >02_SAR732| codons 1-99 PQITLWQRPIVTIKLGGQLKEALLDTGADNTVIEEMNLPGRWKPKMIGGIGGFIKVRQYD EIPIEICGHKAIGTVLVGPTPVNIIGRDLLTQIGCTLNF |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |