Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patBES | 02_BES706 | France | 2002 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI+ AZT | 119 |
| 2 | None | 167 |
| 3 | SQV+ D4T+ 3TC | 104 |
| 4 | AZT+ ABC+ 3TC | 39 |
| 5 | None | 39 |
| 6 | EFV+ DDI+ ABC+ 3TC | 13 |
| 7 | RTV+ AZT+ ABC+ 3TC | 4 |
| 8 | EFV+ DDI+ ABC+ 3TC | 4 |
| 9 | DDI+ D4T+ AZT | 17 |
| 10 | DDI+ AZT+ ABC | 23 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, I15V, E35D, M36I, R41K, R57K, H69K, L89M | G94A |
| >02_BES706| codons 1-99 PQITLWQRPLVTVRVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIACTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R | T215I, K219Q | K103N | A98G | K11T, V35P, K46Q, V60I, T69N, K122E, D123S, I135T, K173S, Q174K, D177E, T200A, Q207A, R211S, F214L |
| >02_BES706| codons 1-240 PISPIETVPVTLKPGMDGPKVKQWPLTEEKIKALPEICTEMEKEGQISKIGPENPYNTPI FAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELRAHLLSWGLITPDQKHQKEPPFLWMGYELHPDKWT |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |