<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
MB_patBES 00_BES703 France 2000 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 DDI+ AZT 119
2 None 167
3 SQV+ D4T+ 3TC 104
4 AZT+ ABC+ 3TC 19

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, I15S, G16R, E35D, M36I, R41K, R57K, H69K, L89M G17R
>00_BES703| codons 1-99
PQITLWQRPLVTVKSRRQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N K219Q     K11T, V35T, T39A, S48A, K49R, V60I, T69N, K122E, D123S, I135T, K173S, D177E, T200A, Q207A, R211S, F214L  
>00_BES703| codons 1-237
PISPIETVPVTLKPGMDGPKVKQWPLTEEKIKALTEICAEMEKEGKIARIGPENPYNTPI
FAIKKKNSNKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSQNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELRAHLLSWGLTTPDQKHQKEPPFLWMGYELHPD

References
Author Title Citation
Montes, B Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. JAIDS, 2004