Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MB_patSAA | 01_SAA704 | France | 2001 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDC+ AZT | 52 |
| 2 | DDC+ AZT+ 3TC | 4 |
| 3 | AZT+ 3TC | 26 |
| 4 | NVP+ DDI+ D4T | 21 |
| 5 | NVP+ DDI | 21 |
| 6 | DDI+ AZT+ 3TC | 17 |
| 7 | NFV+ D4T+ ABC | 4 |
| 8 | SQV+ D4T+ ABC | 17 |
| 9 | None | 74 |
| 10 | EFV+ AZT+ 3TC | 51 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, M184V | K219Q | K103N | K238T | E6K, K11T, K20R, V35T, E36A, T39K, K122E, D123N, I142V, S162Y, K173S, D177E, V179I, I202V, Q207A, R211K, F214L, K223Q, L228H |
| >01_SAA704| codons 1-239 PISPIKTVPVTLKPGMDGPRVKQWPLTEEKIKALTAICKEMEKEGKISKIGPENPYNTPV FAIKKKDSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQYSMTKILEPFRSQNPEIII YQYVDDLYVGSDLEIGQHRTKVEELRAHLLKWGLTTPDQKHQQEPPFHWMGYELHPDTW |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I13V, I15V, E35D, M36I, R41K, H69K, L89M |
| >01_SAA704| codons 1-99 PQITLWQRPIVTVKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Montes, B | Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B. | JAIDS, 2004 |