Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| KDR_pat192 | A0260 | U.S. | 1996 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, K20R, E35D, M36I, R41K, R57K, L63T, E65D, H69HY, I72T, L89M |
| >A0260| codons 4-99 TLWQRPLVTIKVGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYDQIT IDICGYKATGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T39A, K122R, D123E, I135L, I142S, S162Y, K173R, Q207A, R211K |
| >A0260| codons 38-244 CAEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDREFRKYTAFTIPSLNNETPGSRYQYNVLPQGWKGSP AIFQYSMTKILEPFRRQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRAHLLKWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPI |
References
| Author | Title | Citation |
| Kuritzkes, DR | Rate of thymidine analogue resistance mutation accumulation with zidovudine- or stavudine-based regimens. | JAIDS, 2004 |