Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| KDR_pat158 | A0207 | U.S. | 1996 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| N37D, L63V, V77VI |
| >A0207| codons 4-99 TLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMDLPGRWKPKMIGGIGGFIKVRQYDQIV IEICGHKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| A158S, T200I, R211K | K223KI |
| >A0207| codons 38-244 CTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP SIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRIKIEELRQHLLKWGFTTP DKKHQIEPPFLWMGYELHPDKWTVQPI |
References
| Author | Title | Citation |
| Kuritzkes, DR | Rate of thymidine analogue resistance mutation accumulation with zidovudine- or stavudine-based regimens. | JAIDS, 2004 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |