<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
KDR_pat36 A0037 U.S. 1996 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 D4T 24

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  L33I E21EG, I62IV, L63ST, A71T, V77I, V82I  
>A0037| codons 4-99
TLWQRPLVTIKIGGQLKGALLDTGADDTVIEEMNLPGRWKPKMIGGIGGFIKVRQYDQVT
IEICGHKTIGTVLIGPTPINIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        R83K  
>A0037| codons 39-244
TEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPHPA
GLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPA
IFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPD
KKHQKEPPFLWMGYELHPDKWTVQPI

References
Author Title Citation
Kuritzkes, DR Rate of thymidine analogue resistance mutation accumulation with zidovudine- or stavudine-based regimens. JAIDS, 2004
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005