Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PCF_Pat20 | PCF1881 | Italy | 1997 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I13V, L19I, M36L, N37T, I62V, L63P, L89M, C95F |
| >PCF1881| codons 1-99 PQITLWQRPIVTVKIGGQIKEALLDTGADDTVLEELTLPGRWKPKMIGGIGGFIKVRQYD QVPIEICGHKAIGTVLVGPTPVNIIGRNMLTQIGFTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35M, T39A, R83RK, F87FL, I142T, R211K, A272S |
| >PCF1881| codons 1-310 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICAEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKKTQDLWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGTRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGTKALTEVIPLTEEAE LELAENREIL |
References
| Author | Title | Citation |
| Perno, CF | Impact of mutations conferring reduced susceptibility to lamivudine(3TC) on the response to antiretroviral therapy. | Antivir Ther, 2001 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |