Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PCF_Pat6 | PCF1158 | Italy | 1997 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E40D, V60I, R83K, K102KM, D123E, V245E, A272P, I293IV, E297K, L301I |
| >PCF1158| codons 1-310 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTDMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKMKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTKEAE IELAENREIL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12TI, L63ST, I72T, V77I |
| >PCF1158| codons 1-99 PQITLWQRPLVIIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QISIEICGHKATGTVLIGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Perno, CF | Impact of mutations conferring reduced susceptibility to lamivudine(3TC) on the response to antiretroviral therapy. | Antivir Ther, 2001 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |