Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ESH_Pat165 | ESH815 | Uganda | 1998 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | 52 |
| 2 | NVP | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, M36I, P39AS, R41K, D60E, I62V, L63P, I64V |
| >ESH815| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEEINLAGKWKPKMIGGIGGFIKVRQYE QVPVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103KN, Y181YC | K22KN, V35PT, V60I, D121C, K122E, D123E, I135IT, I142IV, T165I, D177E, I178M, T200I, Q207E, R211K, V245I, D250E, A272P, K275Q, K277R, Q278H, L282C, T286A, E297K |
| >ESH815| codons 1-334 PISPIETVPVKLKPGMDGPKVNQWPLTEEKIKALPEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL CEEFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMIKILEPFRKQNPEMVI CQYMDDLYVGSDLEIGQHRIKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIILPEKESWTVNDIQKLVGKLNWASQIYPGIQVRHLCKCLRGAKALTEVIPLTKEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQ |
References
| Author | Title | Citation |
| Eshleman, SH | Characterization of nevirapine resistance mutations in women with subtype A vs. D HIV-1 6-8 weeks after single-dose nevirapine. | JAIDS, 2004 |