Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ESH_Pat162 | ESH525 | Uganda | 1998 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | 52 |
| 2 | NVP | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, L33V, M36I, R57K, L63LP, I64V, H69Y, I72V |
| >ESH525| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVVEEINLPGRWKPKMIGGIGGFIKVKQYD QIPVEICGYKAVGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67DA | V35T, K49R, V60I, S68SG, D121Y, K122E, T139A, D177E, I178M, T200I, Q207E, R211K, V245E, E248D, D250E, A272P, K277R, L282C, T286A, K287R, I293V, E297R, A304E |
| >ESH525| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI FAIKKKAGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL YEDFRKYTAFTIPSINNEAPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMVI YQYMDDLYVGSDLEIGQHRIKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPDKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKCLRGARALTEVVPLTREAE LELEENREILKEPVHGVYYDPSKDLIAEIQKQGQ |
References
| Author | Title | Citation |
| Eshleman, SH | Characterization of nevirapine resistance mutations in women with subtype A vs. D HIV-1 6-8 weeks after single-dose nevirapine. | JAIDS, 2004 |