Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ESH_Pat157 | ESH520 | Uganda | 1998 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | 52 |
| 2 | NVP | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, I15IL, E35D, M36I, N37D, R41K, C67CG, H69K, V82I, L89M |
| >ESH520| codons 1-99 PQITLWQRPLVTVKLGGQLKEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVRQYD QILIEIGGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K11T, K20R, V35T, T39R, V60I, K122E, D123N, K173S, D177E, V179I, I202V, Q207A, R211K, F214L, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, P294T, E312N |
| >ESH520| codons 1-335 PISPIETVPVTLKPGMDGPRVKQWPLTEEKIKALTEICREMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSQNPEIII YQYMDDLYVGSDLEIGQHRTKVEELRAHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVTLTEEAE LELAENREILKNPVHGVYYDPSKDLIAEIQKQGQG |
References
| Author | Title | Citation |
| Eshleman, SH | Characterization of nevirapine resistance mutations in women with subtype A vs. D HIV-1 6-8 weeks after single-dose nevirapine. | JAIDS, 2004 |