Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ESH_Pat151 | ESH596 | Uganda | 1998 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | 52 |
| 2 | NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6D, V35T, E40D, K43N, K49R, V60I, K122E, D123S, I135T, T139TA, I142IV, K173AS, Q174K, D177E, V179I, Q207A, R211S, V245E, D250E, T286A, E291D, V292I, I293V, P294I, E312DN | W88WG |
| >ESH596| codons 1-333 PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTDMENEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFGEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNEAPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIII YQYMDDLYVGSDLEIGQHRTKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVILTEEAE LELAENREILKDPVHGVYYDPSKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10LV, I13V, K14KR, E35D, M36I, R41K, R57K, L63PT, H69K, L89M |
| >ESH596| codons 1-99 PQITLWQRPVVTVRIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Eshleman, SH | Characterization of nevirapine resistance mutations in women with subtype A vs. D HIV-1 6-8 weeks after single-dose nevirapine. | JAIDS, 2004 |