Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ESH_Pat147 | ESH662 | Uganda | 1998 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | 52 |
| 2 | NVP | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, E35D, M36IV, R41K, K45R, L63P, H69K, L89IM |
| >ESH662| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPVNIIGRNILTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K11T, V35T, E40D, K43R, K122E, D123GS, K173L, Q174K, D177E, I178V, V179I, T200A, Q207A, R211S, F214L, V245Q, D250S, A272P, K275Q, K277R, T286A, E291D, V292I, I293V, P294T, E312D, S322A |
| >ESH662| codons 1-334 PISPIETVPVTLKPGMDGPKVKQWPLTEEKIKALTEICTDMEREGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRLKNPEVII YQYMDDLYVGSDLEIGQHRAKIEELRAHLLSWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKSSWTVNDIQKLVGKLNWASQIYPGIQVRQLCKLLRGAKALTDIVTLTEEAE LELAENREILKDPVHGVYYDPAKDLIAEIQKQGQ |
References
| Author | Title | Citation |
| Eshleman, SH | Characterization of nevirapine resistance mutations in women with subtype A vs. D HIV-1 6-8 weeks after single-dose nevirapine. | JAIDS, 2004 |