Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ESH_Pat143 | ESH519 | Uganda | 1998 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | 52 |
| 2 | NVP | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K20R, M36L, N37A, R41K, Q61H, I64V |
| >ESH519| codons 1-99 PQITLWQRPLVTVKIGGQLREALLDTGADDTVLEELALPGKWKPKMIGGIGGFIKVRQYD HILVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35I, V60I, K64KR, K104R, D121Y, K122E, I135R, D177E, I178M, T200I, Q207E, R211K, L228LF, V245K, D250E, I257L, A272P, K277R, L282C, T286A, I293V, K311R, Q334R |
| >ESH519| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPI FAIRKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPL YEDFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMVI YQYMDDLYVGSDLEIGQHRIKIEELREHLLKWGFTTPDKKHQKEPPFFWMGYELHPDKWT VQPIKLPEKESWTVNDLQKLVGKLNWASQIYPGIKVRQLCKCLRGAKALTEVVPLTEEAE LELAENREILREPVHGVYYDPSKDLIAEIQKQGR |
References
| Author | Title | Citation |
| Eshleman, SH | Characterization of nevirapine resistance mutations in women with subtype A vs. D HIV-1 6-8 weeks after single-dose nevirapine. | JAIDS, 2004 |