Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ESH_Pat110 | ESH651 | Uganda | 1998 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | 52 |
| 2 | NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103KN | K11T, V35T, V60I, K122E, D123S, I135T, S162A, K173L, Q174K, D177E, V179I, Q207A, R211S, V245X, E248ED, D250E, A272T, K277R, T286A, E291D, V292VI, I293V, E312N |
| >ESH651| codons 1-334 PISPIETVPVTLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRLKNPEIII YQYMDDLYVGSDLEIGQHRTKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIXLPDKESWTVNDIQKLVGKLNWASQIYTGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENREILKNPVHGVYYDPSKDLIAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, G16A, E35D, M36I, R41K, R57K, H69K, L89M |
| >ESH651| codons 1-99 PQITLWQRPLVTVRIAGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Eshleman, SH | Characterization of nevirapine resistance mutations in women with subtype A vs. D HIV-1 6-8 weeks after single-dose nevirapine. | JAIDS, 2004 |