Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ESH_Pat104 | ESH218 | Uganda | 1998 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | 52 |
| 2 | NVP | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K20KR, M36L, R41K, K43KR, L63P, I64V, K70KR, I72V, V77I |
| >ESH218| codons 1-99 PQITLWQRPLVTVKIGGQLREALLDTGADDTVLEELNLPGKWRPKMIGGIGGFIKVRQYD QIPVEICGHRAVGTVLIGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103KN | E28EA, V35T, E40D, K49R, V60I, K122E, D123N, I135T, S162A, T165X, D177E, Q207E, R211K, F214L, V245K, D250E, A272X, K275KR, K277KR, Q278X, L282C, T286TA, E297A, K311KR |
| >ESH218| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTAEKIKALTEICTDMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQASMXKILEPFRKQNPEIVI YQYMDDLYVGSDLEIGQHRTKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPEKESWTVNDIQKLVGKLNWASQIYXGIRVRXLCKCLRGAKALTEVIPLTAEAE LELAENREILREPVHGVYYDPSKDLIAEIQKQGQG |
References
| Author | Title | Citation |
| Eshleman, SH | Characterization of nevirapine resistance mutations in women with subtype A vs. D HIV-1 6-8 weeks after single-dose nevirapine. | JAIDS, 2004 |