Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ESH_Pat102 | ESH869 | Uganda | 1998 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | 52 |
| 2 | NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103KN, Y181YC | K11KT, V35T, E44ED, K49KR, K122E, D123DG, I135T, I142V, K173S, D177E, V179I, T200X, Q207A, R211RS, V245L, E291D, V292I, I293V, P294T, E312D |
| >ESH869| codons 1-334 PISPIETVPVTLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKDGKISRIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSQNPEIII CQYMDDLYVGSDLEIGQHRXKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPILLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTDIVTLTEEAE LELAENREILKDPVHGVYYDPSKDLIAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, E35D, M36I, R41K, R57K, H69K, L89M |
| >ESH869| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Eshleman, SH | Characterization of nevirapine resistance mutations in women with subtype A vs. D HIV-1 6-8 weeks after single-dose nevirapine. | JAIDS, 2004 |